Dr. Knowler
conducts research on several aspects of type 2 diabetes. He works primarily
with American Indians in the Southwestern United States, but also works on
several multi-center clinical trials and genetics studies involving people
of many ethnic groups in the U.S. His main research areas are the behavioral
and genetic risk factors for type 2 diabetes and its complications, especially
diabetic nephropathy; obesity and its relationship to diabetes; diagnostic
criteria for diabetes; and statistical methods in genetic epidemiology. Current
activities concentrate on the genetics and prevention of diabetes and its
complications. These include pedigree and genetic linkage studies, and the
Diabetes Prevention Program, a multi-center clinical trial of weight loss
in prevention of cardiovascular complications of type 2 diabetes.
UAF
is an affirmative action/equal opportunity employer and educational
institution